Gain of DNA methylation is enhanced in the absence of CTCF at the human retinoblastoma gene promoter

BACKGROUND: Long-term gene silencing throughout cell division is generally achieved by DNA methylation and other epigenetic processes. Aberrant DNA methylation is now widely recognized to be associated with cancer and other human diseases. Here we addressed the contribution of the multifunctional nu...

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Detaylı Bibliyografya
Asıl Yazarlar: Dávalos-Salas, Mercedes, Furlan-Magaril, Mayra, González-Buendía, Edgar, Valdes-Quezada, Christian, Ayala-Ortega, Erandi, Recillas-Targa, Félix
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2011
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3145615/
https://ncbi.nlm.nih.gov/pubmed/21663659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-11-232
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