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Epigenetic silencing of miR-181c by DNA methylation in glioblastoma cell lines

BACKGROUND: Post-transcriptional regulation by microRNAs is recognized as one of the major pathways for the control of cellular homeostasis. Less well understood is the transcriptional and epigenetic regulation of genes encoding microRNAs. In the present study we addressed the epigenetic regulation...

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Publicat a:BMC Cancer
Autors principals: Ayala-Ortega, Erandi, Arzate-Mejía, Rodrigo, Pérez-Molina, Rosario, González-Buendía, Edgar, Meier, Karin, Guerrero, Georgina, Recillas-Targa, Félix
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4794844/
https://ncbi.nlm.nih.gov/pubmed/26983574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2273-6
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