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Epigenetic silencing of miR-181c by DNA methylation in glioblastoma cell lines

BACKGROUND: Post-transcriptional regulation by microRNAs is recognized as one of the major pathways for the control of cellular homeostasis. Less well understood is the transcriptional and epigenetic regulation of genes encoding microRNAs. In the present study we addressed the epigenetic regulation...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Ayala-Ortega, Erandi, Arzate-Mejía, Rodrigo, Pérez-Molina, Rosario, González-Buendía, Edgar, Meier, Karin, Guerrero, Georgina, Recillas-Targa, Félix
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4794844/
https://ncbi.nlm.nih.gov/pubmed/26983574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2273-6
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