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In situ dissection of domain boundaries affect genome topology and gene transcription in Drosophila

Chromosomes are organized into high-frequency chromatin interaction domains called topologically associating domains (TADs), which are separated from each other by domain boundaries. The molecular mechanisms responsible for TAD formation are not yet fully understood. In Drosophila, it has been propo...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Arzate-Mejía, Rodrigo G., Josué Cerecedo-Castillo, Angel, Guerrero, Georgina, Furlan-Magaril, Mayra, Recillas-Targa, Félix
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7021724/
https://ncbi.nlm.nih.gov/pubmed/32060283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-14651-z
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