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Gain of DNA methylation is enhanced in the absence of CTCF at the human retinoblastoma gene promoter
BACKGROUND: Long-term gene silencing throughout cell division is generally achieved by DNA methylation and other epigenetic processes. Aberrant DNA methylation is now widely recognized to be associated with cancer and other human diseases. Here we addressed the contribution of the multifunctional nu...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3145615/ https://ncbi.nlm.nih.gov/pubmed/21663659 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-11-232 |
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