Gain of DNA methylation is enhanced in the absence of CTCF at the human retinoblastoma gene promoter

BACKGROUND: Long-term gene silencing throughout cell division is generally achieved by DNA methylation and other epigenetic processes. Aberrant DNA methylation is now widely recognized to be associated with cancer and other human diseases. Here we addressed the contribution of the multifunctional nu...

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Hlavní autoři: Dávalos-Salas, Mercedes, Furlan-Magaril, Mayra, González-Buendía, Edgar, Valdes-Quezada, Christian, Ayala-Ortega, Erandi, Recillas-Targa, Félix
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2011
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3145615/
https://ncbi.nlm.nih.gov/pubmed/21663659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-11-232
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