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DNA Modeling Reveals an Extended Lac Repressor Conformation in Classic In Vitro Binding Assays
Protein-mediated DNA looping, such as that induced by the lactose repressor (LacI) of Escherichia coli, is a well-known gene regulation mechanism. Although researchers have given considerable attention to DNA looping by LacI, many unanswered questions about this mechanism, including the role of prot...
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| Principais autores: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3145271/ https://ncbi.nlm.nih.gov/pubmed/21806940 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.06.040 |
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