DNA Modeling Reveals an Extended Lac Repressor Conformation in Classic In Vitro Binding Assays

Protein-mediated DNA looping, such as that induced by the lactose repressor (LacI) of Escherichia coli, is a well-known gene regulation mechanism. Although researchers have given considerable attention to DNA looping by LacI, many unanswered questions about this mechanism, including the role of prot...

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Detaylı Bibliyografya
Asıl Yazarlar: Hirsh, Andrew D., Lillian, Todd D., Lionberger, Troy A., Perkins, N.C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Biophysical Society 2011
Konular:
Nucleic Acid
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3145271/
https://ncbi.nlm.nih.gov/pubmed/21806940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.06.040
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