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Mechanism of promoter repression by Lac repressor–DNA loops

The Escherichia coli lactose (lac) operon encodes the first genetic switch to be discovered, and lac remains a paradigm for studying negative and positive control of gene expression. Negative control is believed to involve competition of RNA polymerase and Lac repressor for overlapping binding sites...

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Hlavní autoři: Becker, Nicole A., Peters, Justin P., Lionberger, Troy A., Maher, L. James
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3592455/
https://ncbi.nlm.nih.gov/pubmed/23143103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks1011
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