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Mechanism of promoter repression by Lac repressor–DNA loops
The Escherichia coli lactose (lac) operon encodes the first genetic switch to be discovered, and lac remains a paradigm for studying negative and positive control of gene expression. Negative control is believed to involve competition of RNA polymerase and Lac repressor for overlapping binding sites...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3592455/ https://ncbi.nlm.nih.gov/pubmed/23143103 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks1011 |
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