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The mechanism and high-free-energy transition state of lac repressor–lac operator interaction
Significant, otherwise-unavailable information about mechanisms and transition states (TS) of protein folding and binding is obtained from solute effects on rate constants. Here we characterize TS for lac repressor(R)–lac operator(O) binding by analyzing effects of RO-stabilizing and RO-destabilizin...
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| Veröffentlicht in: | Nucleic Acids Res |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5727403/ https://ncbi.nlm.nih.gov/pubmed/29036376 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx862 |
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