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Use of Urea and Glycine Betaine to Quantify Coupled Folding and Probe the Burial of DNA Phosphates in Lac Repressor – Lac Operator Binding
Thermodynamic analysis of urea-biopolymer interactions and urea effects on folding of proteins and α-helical peptides shows that urea interacts primarily with polar amide surface. Urea is therefore predicted to be a quantitative probe of coupled folding, remodeling and other large-scale changes in t...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2546872/ https://ncbi.nlm.nih.gov/pubmed/16363803 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi0515218 |
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