The mechanism and high-free-energy transition state of lac repressor–lac operator interaction

Significant, otherwise-unavailable information about mechanisms and transition states (TS) of protein folding and binding is obtained from solute effects on rate constants. Here we characterize TS for lac repressor(R)–lac operator(O) binding by analyzing effects of RO-stabilizing and RO-destabilizin...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Sengupta, Rituparna, Capp, Michael W., Shkel, Irina A., Record, M. Thomas
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2017
Témata:
Gene regulation, Chromatin and Epigenetics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5727403/
https://ncbi.nlm.nih.gov/pubmed/29036376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx862
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