Bacterial promoter repression by DNA looping without protein–protein binding competition

The Escherichia coli lactose operon provides a paradigm for understanding gene control by DNA looping where the lac repressor (LacI) protein competes with RNA polymerase for DNA binding. Not all promoter loops involve direct competition between repressor and RNA polymerase. This raises the possibili...

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Hlavní autoři: Becker, Nicole A., Greiner, Alexander M., Peters, Justin P., Maher, L. James
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2014
Témata:
Gene regulation, Chromatin and Epigenetics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4027209/
https://ncbi.nlm.nih.gov/pubmed/24598256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku180
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