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Increased methylation variation in epigenetic domains across cancer types
Tumor heterogeneity is a major barrier to effective cancer diagnosis and treatment. We recently identified cancer-specific differentially DNA-methylated regions (cDMRs) in colon cancer, which also distinguish normal tissue types from each other, suggesting that these cDMRs might be generalized acros...
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Main Authors: | , , , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3145050/ https://ncbi.nlm.nih.gov/pubmed/21706001 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.865 |
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