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UPLC-MS/MS quantification of nanoformulated ritonavir, indinavir, atazanavir, and efavirenz in mouse serum and tissues

Animal pharmacokinetic and tissue distribution assays of antiretroviral therapeutic drugs require accurate drug quantification in biological fluids and tissues. Here we report a simple, rapid, and sensitive ultra performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) method for quan...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Huang, Jiangeng, Gautam, Nagsen, Bathena, Sai Praneeth R, Roy, Upal, McMillan, JoEllyn, Gendelman, Howard E., Alnouti, Yazen
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3144699/
https://ncbi.nlm.nih.gov/pubmed/21752731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2011.06.032
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