UPLC-MS/MS quantification of nanoformulated ritonavir, indinavir, atazanavir, and efavirenz in mouse serum and tissues

Animal pharmacokinetic and tissue distribution assays of antiretroviral therapeutic drugs require accurate drug quantification in biological fluids and tissues. Here we report a simple, rapid, and sensitive ultra performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) method for quan...

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Hlavní autoři: Huang, Jiangeng, Gautam, Nagsen, Bathena, Sai Praneeth R, Roy, Upal, McMillan, JoEllyn, Gendelman, Howard E., Alnouti, Yazen
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3144699/
https://ncbi.nlm.nih.gov/pubmed/21752731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2011.06.032
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