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UPLC-MS/MS quantification of nanoformulated ritonavir, indinavir, atazanavir, and efavirenz in mouse serum and tissues

Animal pharmacokinetic and tissue distribution assays of antiretroviral therapeutic drugs require accurate drug quantification in biological fluids and tissues. Here we report a simple, rapid, and sensitive ultra performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) method for quan...

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書誌詳細
主要な著者: Huang, Jiangeng, Gautam, Nagsen, Bathena, Sai Praneeth R, Roy, Upal, McMillan, JoEllyn, Gendelman, Howard E., Alnouti, Yazen
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3144699/
https://ncbi.nlm.nih.gov/pubmed/21752731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2011.06.032
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