UPLC-MS/MS quantification of nanoformulated ritonavir, indinavir, atazanavir, and efavirenz in mouse serum and tissues

Animal pharmacokinetic and tissue distribution assays of antiretroviral therapeutic drugs require accurate drug quantification in biological fluids and tissues. Here we report a simple, rapid, and sensitive ultra performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) method for quan...

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Autores principales: Huang, Jiangeng, Gautam, Nagsen, Bathena, Sai Praneeth R, Roy, Upal, McMillan, JoEllyn, Gendelman, Howard E., Alnouti, Yazen
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3144699/
https://ncbi.nlm.nih.gov/pubmed/21752731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2011.06.032
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