DAXX/ATRX, MEN1 and mTOR Pathway Genes are Frequently Altered in Pancreatic Neuroendocrine Tumors

Pancreatic Neuroendocrine Tumors (PanNETs) are a rare but clinically important form of pancreatic neoplasia. To explore the genetic basis of PanNETs, we determined the exomic sequences of ten non-familial PanNETs and then screened the most commonly mutated genes in 58 additional PanNETs. Remarkably,...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Jiao, Yuchen, Shi, Chanjuan, Edil, Barish H., de Wilde, Roeland F., Klimstra, David S., Maitra, Anirban, Schulick, Richard D., Tang, Laura H., Wolfgang, Christopher L., Choti, Michael A., Velculescu, Victor E., Diaz, Luis A., Vogelstein, Bert, Kinzler, Kenneth W., Hruban, Ralph H., Papadopoulos, Nickolas
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2011
Θέματα:
Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3144496/
https://ncbi.nlm.nih.gov/pubmed/21252315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1200609
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