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ATRX and DAXX: Mechanisms and Mutations

Recent genome sequencing efforts in a variety of cancers have revealed mutations and/or structural alterations in ATRX and DAXX, which together encode a complex that deposits histone variant H3.3 into repetitive heterochromatin. These regions include retrotransposons, pericentric heterochromatin, an...

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Bibliografiske detaljer
Udgivet i:Cold Spring Harb Perspect Med
Main Authors: Dyer, Michael A., Qadeer, Zulekha A., Valle-Garcia, David, Bernstein, Emily
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5334245/
https://ncbi.nlm.nih.gov/pubmed/28062559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a026567
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