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ATRX and DAXX: Mechanisms and Mutations
Recent genome sequencing efforts in a variety of cancers have revealed mutations and/or structural alterations in ATRX and DAXX, which together encode a complex that deposits histone variant H3.3 into repetitive heterochromatin. These regions include retrotransposons, pericentric heterochromatin, an...
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| Publié dans: | Cold Spring Harb Perspect Med |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Cold Spring Harbor Laboratory Press
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5334245/ https://ncbi.nlm.nih.gov/pubmed/28062559 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a026567 |
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