DAXX/ATRX, MEN1 and mTOR Pathway Genes are Frequently Altered in Pancreatic Neuroendocrine Tumors

Pancreatic Neuroendocrine Tumors (PanNETs) are a rare but clinically important form of pancreatic neoplasia. To explore the genetic basis of PanNETs, we determined the exomic sequences of ten non-familial PanNETs and then screened the most commonly mutated genes in 58 additional PanNETs. Remarkably,...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Jiao, Yuchen, Shi, Chanjuan, Edil, Barish H., de Wilde, Roeland F., Klimstra, David S., Maitra, Anirban, Schulick, Richard D., Tang, Laura H., Wolfgang, Christopher L., Choti, Michael A., Velculescu, Victor E., Diaz, Luis A., Vogelstein, Bert, Kinzler, Kenneth W., Hruban, Ralph H., Papadopoulos, Nickolas
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2011
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3144496/
https://ncbi.nlm.nih.gov/pubmed/21252315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1200609
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