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Structure and Mechanism of the trans-Acting Acyltransferase from the Disorazole Synthase ()

The 1.51 Å resolution X-ray crystal structure of the trans-acyltransferase (AT) from the “AT-less” disorazole synthase (DSZS), and its acetate complex at 1.35 Å resolution, are reported. Separately, comprehensive alanine scanning mutagenesis of one of its acyl carrier protein substrates (ACP1 from D...

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Autores principales: Wong, Fong T., Jin, Xi, Mathews, Irimpan I., Cane, David E., Khosla, Chaitan
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3144309/
https://ncbi.nlm.nih.gov/pubmed/21707057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi200632j
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