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Evidence for angiotensin II type 2 receptor–mediated cardiac myocyte enlargement during in vivo pressure overload

The pathophysiological roles of the angiotensin II type 2 receptor (AT(2)) in cardiac hypertrophy remain unclear. By the targeted deletion of mouse AT(2) we were able to prevent the left ventricular hypertrophy resulting from pressure overload, while cardiac contractile functions remained normal. Th...

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Bibliografske podrobnosti
Main Authors: Senbonmatsu, Takaaki, Ichihara, Sahoko, Price, Edward, Gaffney, F. Andrew, Inagami, Tadashi
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2000
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC314331/
https://ncbi.nlm.nih.gov/pubmed/10930448
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