Evidence for angiotensin II type 2 receptor–mediated cardiac myocyte enlargement during in vivo pressure overload

The pathophysiological roles of the angiotensin II type 2 receptor (AT(2)) in cardiac hypertrophy remain unclear. By the targeted deletion of mouse AT(2) we were able to prevent the left ventricular hypertrophy resulting from pressure overload, while cardiac contractile functions remained normal. Th...

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Détails bibliographiques

Publié dans:	J Clin Invest
Auteurs principaux:	Senbonmatsu, Takaaki, Ichihara, Sahoko, Price, Edward, Gaffney, F. Andrew, Inagami, Tadashi
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Clinical Investigation 2000
Sujets:	Rapid Publication
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC314331/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10930448/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI10037
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