Evidence for angiotensin II type 2 receptor–mediated cardiac myocyte enlargement during in vivo pressure overload

The pathophysiological roles of the angiotensin II type 2 receptor (AT(2)) in cardiac hypertrophy remain unclear. By the targeted deletion of mouse AT(2) we were able to prevent the left ventricular hypertrophy resulting from pressure overload, while cardiac contractile functions remained normal. Th...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Senbonmatsu, Takaaki, Ichihara, Sahoko, Price, Edward, Gaffney, F. Andrew, Inagami, Tadashi
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 2000
Assuntos:	Rapid Publication
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC314331/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10930448/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI10037
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