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Dynamic Interaction of Hsp90 with its Client Protein p53

Although the structure of the molecular chaperone Hsp90 has been extensively characterized by X-ray crystallography, the nature of the interactions between Hsp90 and its client proteins remains unclear. We present results from a series of spectroscopic studies that strongly suggest that these intera...

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Autores principales: Park, Sung Jean, Kostic, Milka, Dyson, H. Jane
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3143201/
https://ncbi.nlm.nih.gov/pubmed/21658391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.05.030
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