A carregar...

Effects of inhibitors on Hsp90's conformational dynamics, cochaperone and client interactions

The molecular chaperone and heat-shock protein Hsp90 has become a central target in anti-cancer therapy. Nevertheless, the effect of Hsp90 inhibition is still not understood at the molecular level, preventing a truly rational drug design. Here we report on the effect of the most prominent drug candi...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Chemphyschem
Main Authors: Schmid, Sonja, Götz, Markus, Hugel, Thorsten
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6525096/
https://ncbi.nlm.nih.gov/pubmed/29677383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cphc.201800342
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!