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Characterization of an Hsp90-independent interaction between the co-chaperone p23 and the transcription factor p53

The cancer-suppressing transcription factor p53 is regulated by a wide variety of cellular factors, including many chaperones. The DNA-binding domain (DBD) of p53 is known to interact with the chaperone Hsp90, but the role of other members of the chaperone network, including co-chaperones such as p2...

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Pubblicato in:Biochemistry
Autori principali: Wu, Huiwen, Hyun, Jashil, Martinez-Yamout, Maria A., Park, Sung Jean, Dyson, H. Jane
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5811392/
https://ncbi.nlm.nih.gov/pubmed/29334217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.7b01076
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