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Reversal of mineral ion homeostasis and soft-tissue calcification of klotho knockout mice by deletion of vitamin D 1α-hydroxylase

Changes in the expression of klotho, a β-glucuronidase, contribute to the development of features that resemble those of premature aging, as well as chronic renal failure. Klotho knockout mice have increased expression of the sodium/phosphate cotransporter (NaPi2a) and 1α-hydroxylase in their kidney...

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Main Authors: Ohnishi, Mutsuko, Nakatani, Teruyo, Lanske, Beate, Razzaque, M. Shawkat
格式: Artigo
語言:Inglês
出版: 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3143194/
https://ncbi.nlm.nih.gov/pubmed/19225558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2009.24
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