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Premature aging in klotho mutant mice: cause or consequence?

Suitable mammalian models for aging with wide range of age-associated pathology are desirable to study molecular mechanisms of human aging. Recent studies have identified that fibroblast growth factor 23 (Fgf-23) null mice and klotho hypomorphs could generate multiple premature aging-like features,...

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Détails bibliographiques
Auteurs principaux: Lanske, Beate, Razzaque, M. Shawkat
Format: Artigo
Langue:Inglês
Publié: 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2896497/
https://ncbi.nlm.nih.gov/pubmed/17353153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.arr.2007.02.002
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