Regulation of C3a Receptor Signaling in Human Mast Cells by G Protein Coupled Receptor Kinases

BACKGROUND: The complement component C3a activates human mast cells via its cell surface G protein coupled receptor (GPCR) C3aR. For most GPCRs, agonist-induced receptor phosphorylation leads to receptor desensitization, internalization as well as activation of downstream signaling pathways such as...

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Hlavní autoři: Guo, Qiang, Subramanian, Hariharan, Gupta, Kshitij, Ali, Hydar
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3143157/
https://ncbi.nlm.nih.gov/pubmed/21799898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0022559
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