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Regulation of C3a Receptor Signaling in Human Mast Cells by G Protein Coupled Receptor Kinases
BACKGROUND: The complement component C3a activates human mast cells via its cell surface G protein coupled receptor (GPCR) C3aR. For most GPCRs, agonist-induced receptor phosphorylation leads to receptor desensitization, internalization as well as activation of downstream signaling pathways such as...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3143157/ https://ncbi.nlm.nih.gov/pubmed/21799898 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0022559 |
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