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Roles for NHERF1 and NHERF2 on the Regulation of C3a Receptor Signaling in Human Mast Cells
BACKGROUND: The anaphylatoxin C3a binds to the G protein coupled receptor (GPCR, C3aR) and activates divergent signaling pathways to induce degranulation and cytokine production in human mast cells. Adapter proteins such as the Na(+)/H(+) exchange regulatory factor (NHERF1 and NHERF2) have been impl...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3527443/ https://ncbi.nlm.nih.gov/pubmed/23284683 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0051355 |
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