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Akt signaling is required for glioblastoma maintenance in vivo

Glioblastoma multiforme (GBM) can be induced in mice through the combined expression of activated forms of KRas and Akt in glial progenitor cells. We have previously demonstrated that KRas is required for the maintenance of these tumors in vivo as inhibition of KRas expression resulted in apoptotic...

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Sonraí Bibleagrafaíochta
Main Authors: Robinson, James P, VanBrocklin, Matthew W, McKinney, Andrea J, Gach, H Michael, Holmen, Sheri L
Formáid: Artigo
Teanga:Inglês
Foilsithe: e-Century Publishing Corporation 2010
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3142953/
https://ncbi.nlm.nih.gov/pubmed/21796274
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