Transcription factors and molecular epigenetic marks underlying EpCAM overexpression in ovarian cancer

BACKGROUND: The epithelial cell adhesion molecule (EpCAM) is overexpressed on carcinomas, and its downregulation inhibits the oncogenic potential of multiple tumour types. Here, we investigated underlying mechanisms of epcam overexpression in ovarian carcinoma. METHODS: Expression of EpCAM and DNA m...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: van der Gun, B T F, de Groote, M L, Kazemier, H G, Arendzen, A J, Terpstra, P, Ruiters, M H J, McLaughlin, P M J, Rots, M G
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2011
Pynciau:
Genetics and Genomics
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3142811/
https://ncbi.nlm.nih.gov/pubmed/21694727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2011.231
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