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Transcription factors and molecular epigenetic marks underlying EpCAM overexpression in ovarian cancer

BACKGROUND: The epithelial cell adhesion molecule (EpCAM) is overexpressed on carcinomas, and its downregulation inhibits the oncogenic potential of multiple tumour types. Here, we investigated underlying mechanisms of epcam overexpression in ovarian carcinoma. METHODS: Expression of EpCAM and DNA m...

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Detalhes bibliográficos
Main Authors: van der Gun, B T F, de Groote, M L, Kazemier, H G, Arendzen, A J, Terpstra, P, Ruiters, M H J, McLaughlin, P M J, Rots, M G
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3142811/
https://ncbi.nlm.nih.gov/pubmed/21694727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2011.231
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