Transcription factors and molecular epigenetic marks underlying EpCAM overexpression in ovarian cancer

BACKGROUND: The epithelial cell adhesion molecule (EpCAM) is overexpressed on carcinomas, and its downregulation inhibits the oncogenic potential of multiple tumour types. Here, we investigated underlying mechanisms of epcam overexpression in ovarian carcinoma. METHODS: Expression of EpCAM and DNA m...

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Autors principals: van der Gun, B T F, de Groote, M L, Kazemier, H G, Arendzen, A J, Terpstra, P, Ruiters, M H J, McLaughlin, P M J, Rots, M G
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2011
Matèries:
Genetics and Genomics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3142811/
https://ncbi.nlm.nih.gov/pubmed/21694727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2011.231
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