Activation of the β globin locus by transcription factors and chromatin modifiers
Locus control regions (LCRs) alleviate chromatin-mediated transcriptional repression. Incomplete LCRs partially lose this property when integrated in transcriptionally restrictive genomic regions such as centromeres. This frequently results in position effect variegation (PEV), i.e. the suppression...
Uloženo v:
| Vydáno v: | EMBO J |
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| Hlavní autoři: | , , , , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group
2000
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC314215/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10990462/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.18.4986 |
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