A haploid genetic screen identifies the major facilitator domain containing 2A (MFSD2A) transporter as a key mediator in the response to tunicamycin

Tunicamycin (TM) inhibits eukaryotic asparagine-linked glycosylation, protein palmitoylation, ganglioside production, proteoglycan synthesis, 3-hydroxy-3-methylglutaryl coenzyme-A reductase activity, and cell wall biosynthesis in bacteria. Treatment of cells with TM elicits endoplasmic reticulum str...

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Detalhes bibliográficos
Main Authors: Reiling, Jan H., Clish, Clary B., Carette, Jan E., Varadarajan, Malini, Brummelkamp, Thijn R., Sabatini, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Feature Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3141996/
https://ncbi.nlm.nih.gov/pubmed/21677192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1018098108
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