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Functional prokaryotic–eukaryotic chimera from the pentameric ligand-gated ion channel family

Pentameric ligand-gated ion channels (pLGICs), which mediate chemo-electric signal transduction in animals, have been recently found in bacteria. Despite clear sequence and 3D structure homology, the phylogenetic distance between prokaryotic and eukaryotic homologs suggests significant structural di...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Duret, Guillaume, Van Renterghem, Catherine, Weng, Yun, Prevost, Marie, Moraga-Cid, Gustavo, Huon, Christèle, Sonner, James M., Corringer, Pierre-Jean
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3141993/
https://ncbi.nlm.nih.gov/pubmed/21730130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1104494108
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