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A yeast-based assay identifies drugs active against human mitochondrial disorders
Due to the lack of relevant animal models, development of effective treatments for human mitochondrial diseases has been limited. Here we establish a rapid, yeast-based assay to screen for drugs active against human inherited mitochondrial diseases affecting ATP synthase, in particular NARP (neuropa...
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| Główni autorzy: | , , , , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
National Academy of Sciences
2011
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3141935/ https://ncbi.nlm.nih.gov/pubmed/21715656 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1101478108 |
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