Experimental Relocation of the Mitochondrial ATP9 Gene to the Nucleus Reveals Forces Underlying Mitochondrial Genome Evolution

Only a few genes remain in the mitochondrial genome retained by every eukaryotic organism that carry out essential functions and are implicated in severe diseases. Experimentally relocating these few genes to the nucleus therefore has both therapeutic and evolutionary implications. Numerous unproduc...

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Detalhes bibliográficos
Main Authors: Bietenhader, Maïlis, Martos, Alexandre, Tetaud, Emmanuel, Aiyar, Raeka S., Sellem, Carole H., Kucharczyk, Roza, Clauder-Münster, Sandra, Giraud, Marie-France, Godard, François, Salin, Bénédicte, Sagot, Isabelle, Gagneur, Julien, Déquard-Chablat, Michelle, Contamine, Véronique, Denmat, Sylvie Hermann-Le, Sainsard-Chanet, Annie, Steinmetz, Lars M., di Rago, Jean-Paul
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3420929/
https://ncbi.nlm.nih.gov/pubmed/22916027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002876
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