Experimental Relocation of the Mitochondrial ATP9 Gene to the Nucleus Reveals Forces Underlying Mitochondrial Genome Evolution

Only a few genes remain in the mitochondrial genome retained by every eukaryotic organism that carry out essential functions and are implicated in severe diseases. Experimentally relocating these few genes to the nucleus therefore has both therapeutic and evolutionary implications. Numerous unproduc...

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Hlavní autoři: Bietenhader, Maïlis, Martos, Alexandre, Tetaud, Emmanuel, Aiyar, Raeka S., Sellem, Carole H., Kucharczyk, Roza, Clauder-Münster, Sandra, Giraud, Marie-France, Godard, François, Salin, Bénédicte, Sagot, Isabelle, Gagneur, Julien, Déquard-Chablat, Michelle, Contamine, Véronique, Denmat, Sylvie Hermann-Le, Sainsard-Chanet, Annie, Steinmetz, Lars M., di Rago, Jean-Paul
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3420929/
https://ncbi.nlm.nih.gov/pubmed/22916027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002876
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