Salt Bridges Overlapping the Gonadotropin-Releasing Hormone Receptor Agonist Binding Site Reveal a Coincidence Detector for G Protein-Coupled Receptor Activation

G protein-coupled receptors (GPCRs) play central roles in most physiological functions, and mutations in them cause heritable diseases. Whereas crystal structures provide details about the structure of GPCRs, there is little information that identifies structural features that permit receptors to pa...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Janovick, Jo Ann, Pogozheva, Irina D., Mosberg, Henry I., Conn, P. Michael
Materialtyp: Artigo
Språk:Inglês
Publicerad: The American Society for Pharmacology and Experimental Therapeutics 2011
Ämnen:
Cellular and Molecular
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3141895/
https://ncbi.nlm.nih.gov/pubmed/21527534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.111.180869
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk