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The PINK1/Parkin pathway regulates mitochondrial dynamics and function in mammalian hippocampal and dopaminergic neurons

PTEN-induced putative kinase 1 (PINK1) and Parkin act in a common pathway to regulate mitochondrial dynamics, the involvement of which in the pathogenesis of Parkinson's disease (PD) is increasingly being appreciated. However, how the PINK1/Parkin pathway influences mitochondrial function is no...

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Autors principals: Yu, Wendou, Sun, Yaping, Guo, Su, Lu, Bingwei
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3140825/
https://ncbi.nlm.nih.gov/pubmed/21613270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddr235
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