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Repair of chromosomal abasic sites in vivo involves at least three different repair pathways
We introduced multiple abasic sites (AP sites) in the chromosome of repair-deficient mutants of Escherichia coli, in vivo, by expressing engineered variants of uracil-DNA glycosylase that remove either thymine or cytosine. After introduction of AP sites, deficiencies in base excision repair (BER) or...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2000
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC314018/ https://ncbi.nlm.nih.gov/pubmed/11032821 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.20.5542 |
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