Repair of U/G and U/A in DNA by UNG2-associated repair complexes takes place predominantly by short-patch repair both in proliferating and growth-arrested cells

Nuclear uracil-DNA glycosylase UNG2 has an established role in repair of U/A pairs resulting from misincorporation of dUMP during replication. In antigen-stimulated B-lymphocytes UNG2 removes uracil from U/G mispairs as part of somatic hypermutation and class switch recombination processes. Using an...

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Main Authors: Akbari, Mansour, Otterlei, Marit, Peña-Diaz, Javier, Aas, Per Arne, Kavli, Bodil, Liabakk, Nina B., Hagen, Lars, Imai, Kohsuke, Durandy, Anne, Slupphaug, Geir, Krokan, Hans E.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2004
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC524284/
https://ncbi.nlm.nih.gov/pubmed/15479784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh872
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