Uracil–DNA glycosylase UNG1 isoform variant supports class switch recombination and repairs nuclear genomic uracil

UNG is the major uracil-DNA glycosylase in mammalian cells and is involved in both error-free base excision repair of genomic uracil and mutagenic uracil-processing at the antibody genes. However, the regulation of UNG in these different processes is currently not well understood. The UNG gene encod...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Sarno, Antonio, Lundbæk, Marie, Liabakk, Nina Beate, Aas, Per Arne, Mjelle, Robin, Hagen, Lars, Sousa, Mirta M L, Krokan, Hans E, Kavli, Bodil
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2019
Fag:
Genome Integrity, Repair and Replication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6511853/
https://ncbi.nlm.nih.gov/pubmed/30838409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz145
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker