Mutagenic specificity of endogenously generated abasic sites in Saccharomyces cerevisiae chromosomal DNA

Abasic [apurinic/apyrimidinic (AP)] sites are common, noncoding DNA lesions. Despite extensive investigation, the mutational pattern they provoke in eukaryotic cells remains unresolved. We constructed Saccharomyces cerevisiae strains in which chromosomal AP sites were generated during normal cell gr...

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Bibliografski detalji
Glavni autori: Auerbach, Paul, Bennett, Richard A. O., Bailey, Elisabeth A., Krokan, Hans E., Demple, Bruce
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2005
Teme:
Biological Sciences
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1308887/
https://ncbi.nlm.nih.gov/pubmed/16314579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0504643102
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