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Mutagenic specificity of endogenously generated abasic sites in Saccharomyces cerevisiae chromosomal DNA
Abasic [apurinic/apyrimidinic (AP)] sites are common, noncoding DNA lesions. Despite extensive investigation, the mutational pattern they provoke in eukaryotic cells remains unresolved. We constructed Saccharomyces cerevisiae strains in which chromosomal AP sites were generated during normal cell gr...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2005
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1308887/ https://ncbi.nlm.nih.gov/pubmed/16314579 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0504643102 |
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