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Roles of Rev1, Pol ζ, Pol32 and Pol η in the bypass of chromosomal abasic sites in Saccharomyces cerevisiae

Translesion synthesis (TLS) on DNA is a process by which potentially cytotoxic replication-blocking lesions are bypassed, but at the risk of increased mutagenesis. The exact in vivo role of the individual TLS enzymes in Saccharomyces cerevisiae has been difficult to determine from previous studies d...

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Detalhes bibliográficos
Main Authors: Auerbach, Paul A., Demple, Bruce
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2796187/
https://ncbi.nlm.nih.gov/pubmed/19901007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/mutage/gep045
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