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Roles of Rev1, Pol ζ, Pol32 and Pol η in the bypass of chromosomal abasic sites in Saccharomyces cerevisiae

Translesion synthesis (TLS) on DNA is a process by which potentially cytotoxic replication-blocking lesions are bypassed, but at the risk of increased mutagenesis. The exact in vivo role of the individual TLS enzymes in Saccharomyces cerevisiae has been difficult to determine from previous studies d...

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Bibliografski detalji
Glavni autori: Auerbach, Paul A., Demple, Bruce
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2796187/
https://ncbi.nlm.nih.gov/pubmed/19901007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/mutage/gep045
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