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Immunoglobulin secretion by B1 cells: Differential intensity and IRF4-dependence of spontaneous IgM secretion by peritoneal and splenic B1 cells

Peritoneal B1 cells are typified by spontaneous, constitutive secretion of IgM natural antibody, detected by ELISPOT assay, among other means. Recently, this key characteristic has been called into question, a reason for which we evaluated the integrity of IgM(+) ELISPOT spots. We found that fixed B...

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Détails bibliographiques
Auteurs principaux: Holodick, Nichol E., Tumang, Joseph R., Rothstein, Thomas L.
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3139744/
https://ncbi.nlm.nih.gov/pubmed/21061433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201040545
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