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Splenic B-1a Cells Expressing CD138 Spontaneously Secrete Large Amounts of Immunoglobulin in Naïve Mice

B-1a cells constitutively secrete natural antibody that provides immediate protection against microbial pathogens and functions homeostatically to speed removal of apoptotic cell debris. Although B-1a cells are especially prominent in the peritoneal and pleural cavities, some B-1a cells reside in th...

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Détails bibliographiques
Auteurs principaux: Holodick, Nichol E., Vizconde, Teresa, Rothstein, Thomas L.
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3975111/
https://ncbi.nlm.nih.gov/pubmed/24734034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2014.00129
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